Conclusion Serum IgA eTG antibody determination can efficiently distinguish UDH from other dermatological itchy diseases and is highly sensitive to gluten‐free diet. (Source: Journal of the European Academy of Dermatology and Venereology)
Conclusion: Oral administration of CTP improves dry skin and normalizes axon-guidance factors in the epidermis in addition to reducing pruritus.
Authors: Pistone G, Doukaki S, Rizzo D, Aricò M, Bongiorno MR Abstract Acquired bilateral nevus of Ota-like macules (ABNOM) or nevus of Hori is a circumscribed dermal melanocytoses characterized by blue-brown mottled hyperpigmentation occurring bilaterally on the forehead, temples, eyelids, nose, with a predilection of malar areas; multiple sites may be involved(1) (fig.1a).
Dendritic cells (DCs) are professional antigen-presenting cells (APCs) capable of initiating innate and acquired immune responses. In peripheral tissues including the skin, they reside as immature DCs and process foreign antigens. After capturing antigens, cutaneous DCs, including Langerhans cells (LCs) and dermal DCs, migrate from the skin to draining lymph nodes.
In this study, to confirm our hypothesis which DKK1 could be involved in the pathogenesis of vitiligo as one of dermal factor, immunohistochemistry and real-time RT-PCR for DKK1, beta-catenin and PAR-2 were performed using vitiligo lesional and non-lesional skin specimens. (Source: Journal of Dermatological Science)
Abstract:Acquired bilateral nevus of Ota–like macules (ABNOM) or nevus of Hori is a circumscribed dermal melanocytoses characterized by blue‐brown mottled hyperpigmentation occurring bilaterally on the forehead, temples, eyelids, nose, with a predilection of malar areas; multiple sites may be involved1 (fig.1a). Clinically it could be hard to distinguish from the congenital bilateral nevus of Ota (type IV nevus of Ota).2We herein report seven cases of ABNOM, periodically evaluated at the Dermatological Department of University of Palermo from April 2004 to June 2010
Conclusion: Our data show that terminal Schwann cells constitute a substantial cell population within the papillary dermis and that both nerve fiber length and Schwann cell numbers vary considerably between different body sites. (Source: Journal of Dermatological Science)
In normal human skin, the basement membrane (BM) lies between the epidermis and dermis, connecting the two compartments tightly and keeping them from direct contact. During skin wound healing, fibroblasts from adjacent intact dermis are activated and migrate to fibrin clots to form granulation tissue, onto which activated keratinocytes at the wound margin migrate, stratify, and differentiate to form a new integument; however, a well-developed BM is not observed until a few months later . During this period, homeostasis between the epidermal and dermal compartments is interrupted and abnormal epidermal–dermal events can ensue.
Conclusions: Our work showed that monitoring the dermal heating status of RF and following up the detailed process of tissue reaction can be imaged and quantified with multiphoton microscopy non-invasively in vivo. (Source: Journal of Dermatological Science)